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Solid preparation has the advantages of high physical and chemical stability, low production cost and convenient taking and carrying. It is the dosage form with the most widely used and most varieties in medicine, and it occupies an important share in pharmaceutical preparations. In order to promote the development of solid preparations, China's solid preparation equipment industry has made rapid progress in recent years, and a number of excellent solid preparation equipment manufacturing enterprises with independent development technology and continuous innovation ability have emerged.

Through years of development, China's solid preparation equipment industry has made rapid progress. However, at present, the granulation process is still the core link of solid preparation production, and few supply enterprises can provide pharmaceutical enterprises with solid preparation granulation line equipment and solutions (including three granulation processes: wet granulation, boiling granulation and dry granulation).

The author learned that Canaan technology is one of the few domestic enterprises with corresponding technical capabilities. It can provide customers with solid preparation granulation line equipment and solutions. It is one of the few domestic suppliers that can provide three granulation processes (wet granulation, boiling granulation and dry granulation) line equipment and solutions. Its products include wet granulation series Boiling drying / granulation series, dry granulation series, lifting series, mixing series, coating series, cleaning series, pharmaceutical containers, etc., covering 96 models and more than 600 specifications.

In addition, the GFL solid preparation production line unit produced by Zhiyang machinery adheres to the traditional granulation process and scientifically and effectively combines wet granulation, boiling drying granulation and wet granulation according to the process characteristics to form a complete solid preparation production linkage line. While retaining the independent use function of each single machine, the linkage unit is equipped with a pipeline hot air curing device for the particle bucket with high viscosity. The production efficiency and automation of the equipment have been greatly improved. Thus, the labor intensity of workers is greatly reduced.

With the continuous improvement of technical content and the continuous shortening of manufacturing cycle, the equipment production of solid preparation production line will continue to develop in the direction of informatization, digitization, refinement, high-speed and automation, and the comprehensive strength and core competitiveness of the industry will be significantly improved. In addition, the development of solid preparation production line equipment should also pay attention to energy conservation and comprehensive utilization of energy, and develop automatic control technology of production line equipment to ensure the realization of optimal operating conditions.

With the market's attention to environmental protection, improving the environmental protection measures of the equipment to reduce the leakage of dust and waste gas will also be the direction of in-depth research on the equipment of solid preparation production line.

For example, the potential safety hazard, quality risk and cost increase caused by the dust produced in the production process of solid preparations are thorny problems faced by all manufacturers, and they are also one of the focuses of the new version of GMP. So, how should enterprises solve these problems? Make GMP certification more smooth? According to the relevant person in charge of Beijing Changfeng Jinding technology, the dust-free operation system of solid preparation can pass through dust-free crushing system, dust-free feeding system, vacuum conveying system, closed automatic batching system and closed